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Recommended positive controls: DHDH tansfected 293T cell.
Predicted reactivity: Dog (84%), Pig (82%), Rabbit (82%), Bovine (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-deoxyglucosone reductase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; DDH; dihydrodiol dehydrogenase (dimeric); Dimeric dihydrodiol dehydrogenase; Hum2DD; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
Gene Aliases: 2DD; DHDH; HUM2DD
UniProt ID: (Human) Q9UQ10
Entrez Gene ID: (Human) 27294
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