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Immunogen sequence: TKTSALSAKK DQPDFISHRM DDVPSHSKAL SDGNGSSGIE WSNVTSSQYD WSQPIVKVDE EPLNLDWGED HDSALDEEED DAVGLVMKST DA
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.
This gene encodes a protein with 12 WD domains. Proteins with WD domains are involved in many functions including participation in signal transduction pathways. Participation of the encoded protein in regulation of the Notch signaling pathway has been demonstrated in vitro using several human cell lines. A gene encoding a similar protein is located on chromosome 5. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dmx-like 2; DmX-like protein 2; rabconnectin 3; Rabconnectin-3
Gene Aliases: DMXL2; KIAA0856; PEPNS; RC3
UniProt ID: (Human) Q8TDJ6
Entrez Gene ID: (Human) 23312
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