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Immunogen sequence: EVEDAILEGN QIERIDQLFA VGGLRHLMFY YQDVEEAETG QLGSLGGVNL VSGKIKKPKV FVTEGNDVAL TGVCVFFIRT DPSKAITPD
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.
This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Axonemal beta dynein heavy chain 5; Ciliary dynein heavy chain 5; Dynein axonemal heavy chain 5; dynein, axonemal, heavy chain 5; dynein, axonemal, heavy polypeptide 5
Gene Aliases: CILD3; DNAH5; DNAHC5; HL1; KIAA1603; KTGNR; PCD
UniProt ID: (Human) Q8TE73
Entrez Gene ID: (Human) 1767
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