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This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 180 kDa protein downstream of CRK; Dedicator of cytokinesis protein 1; dock 180; DOCK180; DOwnstream of CrK; RP11-82L9.1
Gene Aliases: ced5; DOCK1; DOCK180
UniProt ID: (Human) Q14185
Entrez Gene ID: (Human) 1793
Molecular Function:
guanyl-nucleotide exchange factor
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