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DRD3 (extracellular) Antibody (PA5-77390) in IHC (F)
Immunohistochemistry analysis of DRD3 (extracellular) in perfusion-fixed, frozen rat brain. A) Samples were probed with DRD3 (extracellular) polyclonal antibody (Product # PA5-77390) using a dilution of 1:100, and incubated with parvalbumin and DAPI. B) Parvalbumin stained image. C) Merged image of Panels A and B.
Product Details
PA5-77390
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide CGAENSTGVNRARPH, corresponding to amino acid residues 15-29 of rat D3 Dopamine receptor
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2735745
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
Target Information
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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