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This antibody recognizes DTX1 protein (72 kDa) and it's isoforms (about 60 kDa).
Immunogen sequence: MSRPGHGGL MPVNGLGFPP QNVARVVVWE WLNEHSRWRP YTATVCHHIE NVLKEDARGS VVLGQVDAQL VPYIIDLQSM HQFRQDTGTM RPVRRNFYDP SSAPGKGIVW EWENDGGAWT AYDMDICITI QNAYEKQHPW LDLSSLGFCY LIYFNSMSQM NRQTRRRRRL RRRLDLAYPL TVGSIPKSQS WPVGASSGQP CSCQQCLLVN STRAASNAIL ASQRRKAPPA PPLPPPPPPG GPPGALAVRP SATFTGAALW AAPAAGPAEP APPPGAPPRS PGAPGGARTP GQNNLNRPGP QRTTSVSARA SIPPGVPALP VKNLNGTGPV HPALAGMTGI LLCAAGLPVC LTRAPKPILH PPPVSKSDVK PVPGV (1-374 aa encoded by BC048216)
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: deltex 1; deltex 1, E3 ubiquitin ligase; deltex homolog 1; Deltex1; E3 ubiquitin-protein ligase DTX1; fractionated x-irradiation induced transcript 1; FXI-T1; hDTX1; mDTX1; Protein deltex-1; RING-type E3 ubiquitin transferase DTX1
Gene Aliases: DTX1; Fxit1; hDx-1; mKIAA4160
UniProt ID: (Human) Q86Y01, (Mouse) Q61010
Entrez Gene ID: (Human) 1840, (Rat) 687424, (Mouse) 14357
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