Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MPLQVSDYS WQQTKTAVFL SLPLKGVCVR DTDVFCTENY LKVNFPPFLF EAFLYAPIDD ESSKAKIGND TIVFTLYKKE AAMWETLSVT GVDKEMMQRI REKSILQAQE RAKEATEAKA AAKREDQKYA LSVMMKIEEE ERKKIEDMKE NERIKATKAL EAWKEYQRKA EEQKKIQREE KLCQKEKQIK EGRKKIKYKS LTRNLASRNL APKGRNSENI FTEKLKEDSI PAPRSVGSIK INFTPRVFPT ALRESQVAEE EEWLHKQAEA RRAMNTDIAE LCDLKEEEKN PEWLKDKGNK LFATENYLAA INAYNLAIRL NNKMPLLYLN RAVCHLKLKN LHKAIEDSSK EFCSLEGIEC QASEPKLSHH IPSDLHVYIQ MA (1-381 aa encoded by BC062564)
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dynein axonemal assembly factor 4; dynein, axonemal, assembly factor 4; dyslexia susceptibility 1 candidate 1 homolog; Dyslexia susceptibility 1 candidate gene 1 protein; Dyslexia susceptibility 1 candidate gene 1 protein homolog; FLJ37882; MGC70618
Gene Aliases: 1700010I24Rik; b2b811Clo; CILD25; DNAAF4; DYX1; DYX1C1; DYXC1; Edem2; EKN1; RD
UniProt ID: (Human) Q8WXU2, (Rat) Q5VJS5, (Mouse) Q8R368
Entrez Gene ID: (Human) 161582, (Rat) 363096, (Mouse) 67685
Molecular Function:
chaperone
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