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Search Thermo Fisher Scientific
Immunogen sequence: DLDTGNPATD VRYIIGHDAG SWLKIDSRTG EIQFSREFDK KSKYIINGIY TAEILAIDDG SGKTATGTIC IEVPDINDYC PNIFPERRTI CIDSP
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.
Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cadherin family member 13; Desmoglein-4; Desmoglein4
Gene Aliases: CDGF13; CDHF13; DSG4; HYPT6; LAH
UniProt ID: (Human) Q86SJ6
Entrez Gene ID: (Human) 147409
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