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Quantity: 100 µg IgG per vial
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA (cytosine-5)-methyltransferase-like protein 2; DNA methyltransferase 2; DNA methyltransferase homolog MmuIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met-2; RP11-406H21.1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase
Gene Aliases: Dnmt2; Met2; Rnmt2; Trdmt1
UniProt ID: (Mouse) O55055, (Rat) Q4G073
Entrez Gene ID: (Mouse) 13434, (Rat) 291324
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