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            • Primary Antibodies ›
            • EDC3 Antibodies

            Invitrogen

            EDC3 Polyclonal Antibody

            View all (13) EDC3 antibodies

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            Datasheet
            Protocols
            Questions & Answers
            Catalog # PA5-45627
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            Price (USD)
            487.00
            100 µL
             
            Estimated availability date: 07-Jul-2025
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            Cite EDC3 Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            EDC3 Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            EDC3 Antibody (PA5-45627) in WB

            Western blot analysis of human Jurkat cells using an anti-EDC3 polyclonal antibody (Product # PA5-45627).
            View Product

            EDC3 Antibody in Western Blot (WB)

            Product Details

            PA5-45627

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic peptide directed towards the middle region of human EDC3

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.5 mg/mL

            Purification

            Affinity Chromatography

            Storage buffer

            PBS with 2% sucrose

            Contains

            0.09% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2606112

            Product Specific Information

            Peptide sequence: KKSGLKNGQM KNKDDECFGD DIEEIPDTDF DFEGNLALFD KAAVFEEIDT

            Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 87%

            Target Information

            This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: enhancer of mRNA decapping 3 homolog; Enhancer of mRNA-decapping protein 3; hYjeF_N2; hYjeF_N2-15q23; LSM16 homolog; LSM16 homolog (EDC3, S. cerevisiae); yjeF domain containing; YjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; YjeF_N2

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            Gene Aliases: EDC3; LSM16; MRT50; PP844; YJDC; YJEFN2

            View more View less

            UniProt ID: (Human) Q96F86

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            Entrez Gene ID: (Human) 80153

            View more View less

            Function(s)

            mRNA binding protein binding identical protein binding phosphodiesterase decapping endonuclease activity

            Process(es)

            deadenylation-independent decapping of nuclear-transcribed mRNA cytoplasmic mRNA processing body assembly exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay RNA phosphodiester bond hydrolysis, endonucleolytic
            It has to be done as per old AB suggested Products section.
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