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            • Primary Antibodies ›
            • EMAP II Antibodies

            Bioss

            EMAP2 Polyclonal Antibody

            View all (26) EMAP II antibodies
            Datasheet
            Protocols
            Questions & Answers
            Datasheet
            Protocols
            Questions & Answers

            Cite EMAP2 Polyclonal Antibody

            Product Details

            BS-5908R

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:2,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            Assay-dependent
            -

            Immunohistochemistry (Frozen) (IHC (F))

            1:100-1:500
            -

            Immunocytochemistry (ICC/IF)

            1:50-1:200
            -

            ELISA (ELISA)

            1:500-1:1,000
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            KLH conjugated synthetic peptide derived from human EMAP2, amino acids 201-300.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A

            Storage buffer

            0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

            Contains

            0.02% ProClin 300

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; ARS inducible multifunctional protein 1; ARS-interacting multifunctional protein 1; endothelial monocyte activating polypeptide 2; endothelial monocyte-activating polypeptide 2; endothelial-monocyte activating polypeptide II; mca1; Multisynthase complex auxiliary component p43; multisynthetase complex auxiliary component p43; small inducible cytokine subfamily E, member 1; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)

            View more View less

            Gene Aliases: 9830137A06Rik; AIMP1; AIMP1/p43; EMAP2; EMAPII; HLD3; p43; SCYE1

            View more View less

            UniProt ID: (Human) Q12904

            View more View less

            Entrez Gene ID: (Human) 9255, (Mouse) 13722, (Rat) 114632

            View more View less

            Function(s)

            tRNA binding cytokine activity protein binding protein homodimerization activity GTPase binding RNA binding translational protein

            Process(es)

            angiogenesis negative regulation of endothelial cell proliferation glucose metabolic process tRNA aminoacylation for protein translation apoptotic process chemotaxis inflammatory response cell adhesion signal transduction cell-cell signaling response to wounding leukocyte migration defense response to virus carbohydrate metabolic process translation negative regulation of angiogenesis blood vessel morphogenesis
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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