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The ectoderm-neural cortex-1 (ENC-1) protein is an early and highly specific marker of neural induction in vertebrates. It is a kelch family related protein that functions as an actin-binding protein and has been suggested to be involved in the organization of the actin cytoskeleton during neural fate specification and development of the nervous system. ENC-1 has also been shown to be required for adipocyte differentiation when cytoskeletal reorganization and cell shape change from fibroblastic preadipocytes to spherical adipocytes occur.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ectoderm-neural cortex protein 1; ectodermal-neural cortex 1 (with BTB domain); ectodermal-neural cortex 1 (with BTB-like domain); ENC-1; FLJ39259; kelch-like 35; kelch-like 37; kelch-like family member 37; Kelch-like protein 37; Nuclear matrix protein NRP/B; nuclear restrict protein in brain; nuclear restricted protein, BTB domain-like (brain); p53-induced gene 10 protein; tumor protein p53 inducible protein 10
Gene Aliases: CCL28; ENC-1; ENC1; KLHL35; KLHL37; NRPB; PIG10; TP53I10
UniProt ID: (Human) O14682, (Mouse) O35709
Entrez Gene ID: (Human) 8507, (Mouse) 13803, (Rat) 294674
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