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Bioss

EPHB3/Eph receptor B3 Polyclonal Antibody

View all (29) EphB3 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Product Details

BS-11281R

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:1,000

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500

Immunocytochemistry (ICC/IF)

1:100-1:500

ELISA (ELISA)

1:500-1:1,000

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human EPHB3/Eph receptor B3, amino acids 121-220.

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

EPHB3 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Developmental kinase 5; EK2; Embryonic kinase 2; EPH-like kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; Ephrin type-B receptor 3; human embryo kinase 2; mDK-5; Tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO6

Gene Aliases: AW456895; Cek10; EK2; EPHB3; ETK2; HEK2; MDK5; Sek4; TYRO6

UniProt ID: (Human) P54753, (Mouse) P54754

Entrez Gene ID: (Human) 2049, (Mouse) 13845, (Rat) 287989

Function(s)

ephrin receptor activity ATP binding axon guidance receptor activity nucleotide binding protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity transmembrane-ephrin receptor activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups transmembrane signal receptor

Process(es)

angiogenesis urogenital system development axon guidance axonal fasciculation cell migration peptidyl-tyrosine phosphorylation central nervous system projection neuron axonogenesis corpus callosum development regulation of cell-cell adhesion retinal ganglion cell axon guidance substrate adhesion-dependent cell spreading regulation of GTPase activity protein autophosphorylation ephrin receptor signaling pathway thymus development digestive tract morphogenesis regulation of axonogenesis positive regulation of synapse assembly palate development dendritic spine development dendritic spine morphogenesis protein phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway multicellular organism development nervous system development phosphorylation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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