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Immunogen sequence: KFLCCQQSCK AAPGCTLWEA YANLHTAVNE EKHRVPTFPD RVLKIPRAVP VLKMDAPSSS TTLAQYDNES KKNYGSQPPS SSTSLAQYDS NSKKIYGSQP NFNMQYIPRE DFPDWWQVR
Bone marrow tyrosine kinase (BMX) is a non-receptor tyrosine kinase that belongs to the SRC-related TEC subfamily of tyrosine kinases. It is an important regulator of various cellular processes including apoptosis, cell survival, cellular differentiation, cell migration, and transformation. One family of nonreceptor TKs includes the genes TEC (MIM 600583), TXK (MIM 600058), ITK (MIM 186973), and BTK (MIM 300300). All of these proteins are homologs of the Drosophila Src28 TK and contain an SH3 and SH2 domain upstream of the TK domain.[supplied by OMIM].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bone marrow tyrosine kinase gene in chromosome X protein; BTK-like on X chromosome; Cytoplasmic tyrosine-protein kinase BMX; epa3; Epithelial and endothelial tyrosine kinase; ETK; Etk/Bmx cytosolic tyrosine kinase; NTK38; NTK38 tyrosine kinase
Gene Aliases: BMX; ETK; PSCTK2; PSCTK3
UniProt ID: (Human) A6NIH9
Entrez Gene ID: (Human) 660
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