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            • Primary Antibodies ›
            • ETS2 Antibodies

            Invitrogen

            ETS2 Monoclonal Antibody (OTI1H4)

            View all (25) ETS2 antibodies
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            Catalog # MA5-26121
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            100 µL
             
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            Cite ETS2 Monoclonal Antibody (OTI1H4)

            • Antibody Testing Data (9)
            Application
            ETS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 9

            ETS2 Antibody (MA5-26121) in IHC (P)

            Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a ETS2 monoclonal antibody (Product # MA5-26121).
            View Product

            ETS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ETS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ETS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ETS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            ETS2 Antibody in Western Blot (WB)
            ETS2 Antibody in Western Blot (WB)
            ETS2 Antibody in Western Blot (WB)
            ETS2 Antibody in Western Blot (WB)
            ETS2 Antibody in Western Blot (WB)

            Product Details

            MA5-26121

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:4,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:150
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Mouse / IgG2b

            Class

            Monoclonal

            Type

            Antibody

            Clone

            OTI1H4

            Immunogen

            Human recombinant protein fragment corresponding to amino acids 90-349 of ETS2 produced in E.coli
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Affinity Chromatography

            Storage buffer

            PBS, pH 7.3, with 1% BSA, 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2723146

            Target Information

            ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: oncogene ETS-2; Protein C-ets-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2

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            Gene Aliases: ETS2; ETS2IT1

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            UniProt ID: (Human) A6NM68

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            Entrez Gene ID: (Human) 2114

            View more View less

            Function(s)

            RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding glucocorticoid receptor binding winged helix/forkhead transcription factor

            Process(es)

            negative regulation of transcription from RNA polymerase II promoter skeletal system development ectodermal cell fate commitment transcription, DNA-templated mesoderm development cell differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter primitive streak formation
            It has to be done as per old AB suggested Products section.
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