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Invitrogen
ETV6 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 2
ETV6 Antibody (PA5-81865)
Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of ETV6 was observed specifically in U2OS cells and in Caco-2 cells using anti-ETV6 Polyclonal Antibody (Product #PA5-81865) in western blot. The relative expression levels of ETV6 within each cell line is shown using RNA-Seq. {RE}
Product Details
PA5-81865
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ETV6. Recombinant protein control fragment (Product #RP-93720).
Conjugate
Form
Liquid
Concentration
0.08 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789026
Product Specific Information
Immunogen sequence: NGKALLLLTK EDFRYRSPHS GDVLYELLQH ILKQRKPRIL FSPFFHPGNS IHTQPEVILH QNHEEDNCVQ RTPRPSVDNV HHNPPTIELL HRSRSPITTN HRPSPDPEQR PLRSPLDNMI R
Target Information
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and Maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CGI-108; CSL4; Csl4p; ETS translocation variant 6; ets variant gene 6 (TEL oncogene); ETS-related protein Tel1; hCsl4p; p13; RP11-452K12.9; SKI4; Ski4p; Tel; TEL1 oncogene; Transcription factor ETV6
Gene Aliases: ETV6; TEL; TEL/ABL; TEL1; THC5
UniProt ID: (Human) P41212
Entrez Gene ID: (Human) 2120
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein domain specific binding
winged helix/forkhead transcription factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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