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Bioss
EV71 polyprotein 3D Polyclonal Antibody
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Application
FIGURE: 1 / 1
EV71 polyprotein 3D Antibody (BS-2339R) in ELISA
Antigen: bs-2339P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat Anti-Rabbit IgG (bs-0295G-HRP) at 1:5000; TMB staining; Read the data in Microplate Reader by 450nm.
Product Details
BS-2339R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from EV71 polyprotein 3D.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
EV71 is a positive-sense single-stranded RNA virus of the Picornaviridae family. It is known to cause hand, foot, and mouth disease and various neurological pathological conditions, such as aseptic meningitis and ataxia. EV71 is shown to utilize host UDP-glucose glycoprotein glucosyltransferase 1 (UGGT1) to enhance viral replication and virulence. It forms replication complexes (RCs) on cellular membranes that contain a mix of host and viral proteins to facilitate viral replication. During infection viral RNA replication occurs on the cytoplasmic surfaces of single-membrane vesicles derived from the endoplasmic reticulum, and the membranes can serve to accelerate RC assembly during positive-strand genomic RNA replication. It has been shown that 3D polymerase, an RNA-dependent RNA polymerase that is encoded in the P3 viral genome region, plays a key role in EVA71 replication. Neural progenitor cells are shown to be prone to EV71 infection and that these stem cells can support the active replication of this virus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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