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FIGURE: 1 / 2
Western blot detects a band at ~87 kDa.
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exocyst complex component 3; Exocyst complex component Sec6; LIM/homeobox protein Lhx2 pseudogene; rSec6; Sec 6 homolog; Sec6 protein; SEC6-like 1
Gene Aliases: 2810050O03Rik; E430013E20Rik; EXOC3; I79_024581; rSec6; SEC6; SEC6L1; Sec6p
UniProt ID: (Human) O60645, (Bovine) Q0V8C2, (Rat) Q62825, (Mouse) Q6KAR6
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