Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MAPAGNNKF SSKAMAETFY LSNIVPQDFD NNSGYWNRIE MYCRELTERF EDVWVVSGPL TLPQTRGDGK KIVSYQVIGE DNVAVPSHLY KVILARRSSV STEPLALGAF VVPNEAIGFQ PQLTEFQVSL QDLEKLSGLV FFPHLDRTSD IRNICSVDTC KLLDFQEFTL YLSTRKIEGA RSVLRLEKIM ENLKNAEIEP DDYFMSRYEK KLEELKAKEQ SGTQIRKPS (141-368 aa encoded by BC104212)
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endo G-like 1; Endonuclease G-like 1; endonuclease G-like 2; Nuclease EXOG, mitochondrial
Gene Aliases: AW557704; ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-B; ENGLA; ENGLB; EXOG
UniProt ID: (Human) Q9Y2C4, (Mouse) Q8C163
Entrez Gene ID: (Human) 9941, (Mouse) 208194, (Rat) 301062
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