Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MAAGFKTVE PLEYYRRFLK ENCRPDGREL GEFRTTTVNI GSISTADGSA LVKLGNTTVI CGVKAEFAAP STDAPDKGYV VPNVDLPPLC SSRFRSGPPG EEAQVASQFI ADVIENSQII QKEDLCISPG KLVWVLYCDL ICLDYDGNIL DACTFALLAA LKNVQLPEVT INEETALAEV NLKKKSYLNI RTHPVATSFA VFDDTLLIVD PTGEEEHLAT GTLTIVMDEE GKLCCLHKPG GSGLTGAKLQ DCMSRAVTRH KEVKKLMDEV IKSMKPK (1-276 aa encoded by BC020773)
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CBP-interacting protein 3; Exosome complex component RRP43; exosome complex exonuclease RRP43; Exosome component 8; OIP-2; Opa interacting protein 2; Opa-interacting protein 2; p9; Ribosomal RNA-processing protein 43; RP11-421P11.3
Gene Aliases: 2310032N20Rik; bA421P11.3; CIP3; EAP2; EXOSC8; mKIAA4013; OIP2; p9; PCH1C; RRP43; Rrp43p
UniProt ID: (Human) Q96B26, (Mouse) Q9D753
Entrez Gene ID: (Human) 11340, (Mouse) 69639, (Rat) 295050
Molecular Function:
RNA metabolism protein
exoribonuclease
nucleic acid metabolism protein
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