Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 10
Positive Control: HCT116 cell lysate, K562 cell lysate, PANC-1 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, rat large intestine tissue, human colon tissue, mouse large intestine tissue.
Subcellular Location: Nucleus.
Tissue Specificity: Tissue enhanced (retina).
Sequence Similarities: 97% Mouse/Rat.
EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Enhancer of zeste homolog 1; ENX-2; Histone-lysine N-methyltransferase EZH1
Gene Aliases: ENX-2; Enx2; EZH1; KIAA0388; KMT6B
UniProt ID: (Human) Q92800, (Mouse) P70351
Entrez Gene ID: (Human) 2145, (Rat) 303547, (Mouse) 14055
Molecular Function:
histone modifying enzyme
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