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Product Details
BS-6635R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Elongin A, amino acids 701-798.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EloA; EloA2; Elongin 110 kDa subunit; Elongin A; Elongin A2; Elongin-A; Elongin-A2; RNA polymerase II transcription factor elongin subunit A (110 kDa); RNA polymerase II transcription factor SIII subunit A; RNA polymerase II transcription factor SIII subunit A1; RNA polymerase II transcription factor SIII subunit A2; SIII p110; TCEB3B; TCEB3L; transcription elongation factor (SIII) elongin A2 elongin A2; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); transcription elongation factor B alpha subunit; Transcription elongation factor B polypeptide 3; Transcription elongation factor B polypeptide 3B
Gene Aliases: 110kDa; AA408125; El; ELOA; ELOA2; HsT832; MSTP059; SIII; SIII p110; TCEB3; TCEB3A; TCEB3B; TCEB3L
UniProt ID: (Human) Q14241, (Human) Q8IYF1, (Mouse) Q8CB77
Entrez Gene ID: (Human) 6924, (Human) 51224, (Mouse) 27224, (Rat) 25562
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
transcription from RNA polymerase II promoter
regulation of DNA-templated transcription, elongation
translational elongation
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