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The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EEN; EEN fusion partner of MLL; endophilin A2; Endophilin-2; Endophilin-A2; extra 11-19 leukemia fusion; Extra eleven-nineteen leukemia fusion gene protein; MGC111371; SH3 domain containing GRB2 like 1; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1; SH3-containing Grb-2-like 1 protein; SH3-domain GRB2-like 1
Gene Aliases: CNSA1; EEN; SH3D2B; SH3GL1; SH3P8
UniProt ID: (Human) Q99961
Entrez Gene ID: (Human) 6455
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