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Product Details
PA5-79211
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Eph receptor B3 (982-998aa SIQDMRLQMNQTLPVQV).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746327
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
EPHB3 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Developmental kinase 5; EK2; Embryonic kinase 2; EPH-like kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; Ephrin type-B receptor 3; human embryo kinase 2; mDK-5; Tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO6
Gene Aliases: AW456895; Cek10; EK2; EPHB3; ETK2; HEK2; MDK5; Sek4; TYRO6
UniProt ID: (Human) P54753, (Mouse) P54754
Entrez Gene ID: (Human) 2049, (Mouse) 13845, (Rat) 287989
ephrin receptor activity
ATP binding
axon guidance receptor activity
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
transmembrane-ephrin receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
transmembrane signal receptor
angiogenesis
urogenital system development
axon guidance
axonal fasciculation
cell migration
peptidyl-tyrosine phosphorylation
central nervous system projection neuron axonogenesis
corpus callosum development
regulation of cell-cell adhesion
retinal ganglion cell axon guidance
substrate adhesion-dependent cell spreading
regulation of GTPase activity
protein autophosphorylation
ephrin receptor signaling pathway
thymus development
digestive tract morphogenesis
regulation of axonogenesis
positive regulation of synapse assembly
palate development
dendritic spine development
dendritic spine morphogenesis
protein phosphorylation
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
nervous system development
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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