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Immunogen sequence: QEITATLEAL CGIAEATQID NVAILFNFLM DFLTNCIGLM EVYKNTPETV NLIIEVFVEV AHKQICYLGE SKAMNLYEAC LTLLQVYSKN NLGRQRIDVT AEEEQYQDLL LIMELLTNLL SKEFIDFSDT DEVFRGHEPG QAANRSVSAA DVVLYGVNLI LPLMSQDLLK FPTLCNQYYK LITFICEIFP EKIPQLPEDL FKSLMYSLEL GMTSMSSEVC QLCLEALTPL AEQCAKAQET DSPLFLATRH FLKLVFDMLV LQKHNTEMTT AAGEAFYTLV CLHQAEYSEL VETLLSSQQD PVIYQRLADA FNKLTASSTP PTLDRKQKMA FLKSLEEFMA NVGGLLCVK
Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-4 is a novel mammalian member of this family. It is a RanGTP-binding protein consisting of N-terminal RanGTP-binding motif. It functions as a nuclear export receptor for eIF-5A and also might function as an export adapter in RNA export. It is also involved in nuclear export of Smad3 and regulation of Smad signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exp4; Exportin-4; FLJ13046
Gene Aliases: B430309A01Rik; exp4; KIAA1721; mKIAA1721; XPO4
UniProt ID: (Human) Q9C0E2, (Mouse) Q9ESJ0
Entrez Gene ID: (Human) 64328, (Mouse) 57258
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