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Fatty acid-binding protein 9 (FABP9), also known as testis FABP, is a gene located on chromosome 8q21.1 that encodes a protein primarily expressed in the testis, where it plays a critical role in fatty acid metabolism and transport. FABP9 is part of a larger family of fatty acid-binding proteins that facilitate the intracellular movement and storage of lipids, impacting cellular signaling and energy homeostasis. Structurally, FABP9 is adapted to bind long-chain fatty acids and other hydrophobic molecules, contributing to the regulation of lipid dynamics within spermatogenic cells. The expression of FABP9 is crucial during spermatogenesis, influencing sperm maturation and fertility. Beyond its reproductive role, variations in FABP9 have been studied in relation to metabolic disorders, linking its lipid regulatory functions to broader physiological processes. Research continues to explore FABP9's potential involvement in systemic lipid metabolism and its implications for diseases associated with lipid dysregulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 15 kDa perforatorial protein; FABP-9; fatty acid binding protein 9, testis; Fatty acid-binding protein 9; lipid-binding protein; PERF 15; T-FABP; testis fatty acid binding protein; testis lipid binding protein; Testis lipid-binding protein; Testis-type fatty acid-binding protein; TLBP
Gene Aliases: 1700007P10Rik; FABP9; PERF; PERF15; T-FABP; TLBP
UniProt ID: (Human) Q0Z7S8, (Mouse) O08716, (Rat) P55054
Entrez Gene ID: (Human) 646480, (Mouse) 21884, (Rat) 64822
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