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Bioss

FAF1 Polyclonal Antibody

View all (41) FAF1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)

Application

FAF1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 2

FAF1 Antibody (BS-1348R) in IHC (P)

Formalin-fixed and paraffin embedded rat pancreas tissue labeled with Anti-FAF1 Polyclonal Antibody, Unconjugated (bs-1348R) followed by conjugation to the secondary antibody and DAB staining.

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Product Details

BS-1348R

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:400

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500

Immunocytochemistry (ICC/IF)

1:50-1:200

Flow Cytometry (Flow)

1:20-1:100

ELISA (ELISA)

1:500-1:1,000

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human FAF1, amino acids 551-650.

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; hFAF1; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A

Gene Aliases: AA408698; CGI-03; Dffrx; FAF1; Fam; hFAF1; HFAF1s; UBXD12; UBXN3A

UniProt ID: (Human) Q9UNN5, (Mouse) P54731, (Rat) Q924K2

Entrez Gene ID: (Human) 11124, (Mouse) 14084, (Rat) 140657

Function(s)

protein binding protein kinase regulator activity protein kinase binding protein domain specific binding heat shock protein binding ubiquitin protein ligase binding ubiquitin binding NF-kappaB binding molecular_function

Process(es)

apoptotic process cytoplasmic sequestering of NF-kappaB cell death positive regulation of cell death regulation of cell adhesion positive regulation of protein complex assembly regulation of protein catabolic process positive regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process regulation of protein kinase activity positive regulation of extrinsic apoptotic signaling pathway via death domain receptors biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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