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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
FAM173B is a 233 amino acid single-pass membrane protein that is encoded by a gene that maps to human chromosome 5, which makes up about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP synthase subunit C lysine N-methyltransferase; family with sequence similarity 173, member B; hFAM173B; mFam173b; protein FAM173B; Protein N-lysine methyltransferase FAM173B
Gene Aliases: A930016P21Rik; AA987072; ATPSCKMT; FAM173B; JS-2; RGD1560629
UniProt ID: (Human) Q6P4H8, (Mouse) Q9D1Z3, (Rat) D3ZLY0
Entrez Gene ID: (Human) 134145, (Mouse) 68073, (Rat) 499561
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