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Immunogen sequence: DTDWLLAGNRT QSAHCHCGDH VRDSMHIYGS YSPTICTRRV LSAGKGKNKL PWENEQPGIM GENQTSTSKD IEQFSTYDFI PSAKLKLSQG MPVNDDLCFS
Highest antigen sequence identity to the following orthologs - mouse 83%, rat 85%.
Required for normal structure and function of primary cilia. Plays a role in the organization of axoneme microtubule bundles in primary cilia. Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Crescerin-1; family with sequence similarity 179, member B; Protein FAM179B; TOG array regulator of axonemal microtubules protein 1
Gene Aliases: FAM179B; KIAA0423; TOGARAM1
UniProt ID: (Human) Q9Y4F4
Entrez Gene ID: (Human) 23116
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