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FBP1 Antibody (MA5-49953) in IHC (P)
Immunohistochemistry analysis with a FBP1 monoclonal antibody (Product # MA5-49953) using a dilution of 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was in... View More
Product Details
MA5-49953
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4G3
Immunogen
A synthesized peptide derived from human FBP1
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_3092779
Target Information
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; EC 3.1.3.11; FBP 1; FBPase 1; fructose-1; Fructose-1,6-bisphosphatase 1; growth-inhibiting protein 17; Liver FBPase
Gene Aliases: FBP; FBP1
UniProt ID: (Human) P09467
Entrez Gene ID: (Human) 2203
fructose metabolic process
fructose catabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
regulation of gluconeogenesis
dephosphorylation
negative regulation of cell growth
cellular response to drug
negative regulation of glycolytic process
negative regulation of Ras protein signal transduction
protein homotetramerization
cellular response to magnesium ion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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