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Application
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FCRL1 Antibody (MA5-24356) in Flow
Flow cytometry of FCRL1 in Mouse splenocytes were stained with Rat Anti-Mouse B220/CD45R APC-conjugated Monoclonal Antibody. Samples were incubated in either (A) FCRL1 monoclonal antibody (Product # MA5-24356) or (B) Rat Anti-Mouse FCRL1/FcRH1 Monoclonal Antibody followed by Phycoerythrin-conjugated Anti-Rat IgG Secondary Antibody.
Product Details
MA5-24356
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
745916
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse FCRL1/FcRH1 Ala17-Ser219
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606495
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
Fc receptor-like 1 (FCRL1) is a gene situated on chromosome 1q23, encoding a protein that is part of the Fc receptor-like family, which shares structural similarities with classical Fc receptors involved in immune responses. FCRL1 is predominantly expressed in B lymphocytes and is thought to play a role in the regulation of immune functions, particularly those associated with B cell development and differentiation. Although its precise biological function is not fully understood, it is believed to act as an immunomodulatory receptor that could influence B cell signaling pathways. The expression patterns of FCRL1 suggest possible involvement in autoimmune disorders and immune system modulation, potentially contributing to pathological conditions when dysregulated. Research into FCRL1 and other Fc receptor-like proteins continues to explore their contributions to immune homeostasis and potential as therapeutic targets in diseases involving B cell dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BXMAS1-like protein 1; BXMAS1-like protein 1b; CD307a; CD307a antigen; Fc receptor homolog 1; Fc receptor-like protein 1; FcR-like protein 1; FcRH1; FCRH1DKFZp667O1421; IFGP family protein 1; mBXMH1; mIFGP1
Gene Aliases: A230020G22Rik; Bxmas1; Bxmh1; Bxmh1b; Fcrh1; Fcrh1l; Fcrh1s; Fcrl1; Ifgp1
UniProt ID: (Mouse) Q8R4Y0
Entrez Gene ID: (Mouse) 229499
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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