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Invitrogen
FCRL2 Monoclonal Antibody (7B12A3)
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Product Details
MA5-38482
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
7B12A3
Immunogen
Purified recombinant fragment of human CD307B (aa: extra 20-253) expressed in E. Coli.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2898395
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
The FCRL2 gene encodes the protein Fc receptor-like 2, which is part of the Fc receptor-like family involved in immune system regulation. FCRL2 is primarily expressed on the surface of B lymphocytes, where it contributes to the modulation of B cell activation and immune responses. As a member of the Fc receptor-like family, FCRL2 is thought to play roles in signaling pathways that influence B cell development, differentiation, and antibody production. It may act as a regulatory receptor that balances immune activation and inhibition, thereby contributing to immune homeostasis and prevention of autoimmunity. The expression of FCRL2 can impact conditions such as autoimmune diseases and B cell-related disorders, where dysregulation of B cell signaling is evident. Research into FCRL2 is ongoing to explore its specific ligand interactions and functional mechanisms, aiming to understand its potential as a therapeutic target for modulating immune responses in diseases characterized by B cell dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD307b; Fc receptor homolog 2; Fc receptor-like 2; Fc receptor-like protein 2; FcR-like protein 2; FcRH2; IFGP family protein 4; immune receptor translocation-associated protein 4; Immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; RP11-367J7.6; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1
Gene Aliases: CD307b; FCRH2; FCRL2; IFGP4; IRTA4; SPAP1; SPAP1A; SPAP1B; SPAP1C; UNQ9236/PRO31998
UniProt ID: (Human) Q96LA5
Entrez Gene ID: (Human) 79368
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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