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FGF20 Antibody (BS-5772R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with FGF20 Polyclonal Antibody, Unconjugated (bs-5772R) at 1:400 overnight at 4°C, DAB staining.
Product Details
BS-5772R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human FGF20, amino acids 25-211.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
FGF-20 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through FGFR 2c and 3c, and is expressed during limb and brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; FGF-20; Fibroblast growth factor; Fibroblast growth factor 20
Gene Aliases: FGF-20; FGF20; RHDA2
UniProt ID: (Human) Q9NP95, (Rat) Q9EST9, (Mouse) Q9ESL9
Entrez Gene ID: (Human) 26281, (Rat) 66017, (Mouse) 80857
protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
fibroblast growth factor receptor binding
growth factor activity
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
receptor binding
growth factor
intercellular signal molecule
MAPK cascade
signal transduction
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
regulation of cardiac muscle cell proliferation
inner ear receptor cell differentiation
positive regulation of ERK1 and ERK2 cascade
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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