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Product Details
24725-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FGFBP3 Fusion Protein Ag20573 (1-258 aa encoded by BC025966)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTPPKLRAS LSPSLLLLLS GCLLAAARRE KGAASNVAEP VPGPTGGSSG RFLSPEQHAC SWQLLLPAPE AAAGSELALR CQSPDGARHQ CAYRGHPERC AAYAARRAHF WKQVLGGLRK KRRPCHDPAP LQARLCAGKK GHGAELRLVP RASPPARPTV AGFAGESKPR ARNRGRTRER ASGPAAGTPP PQSAPPKENP SERKTNEGKR KAALVPNEER PMGTGPDPDG LDGNAELTET YCAEKWHSLC NFFVNFWNG (1-258 aa encoded by BC025966 )
Target Information
FGFBP3 is a heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF-binding protein 3; FGF-BP3; FGFBP-3; Fibroblast growth factor-binding protein 3
Gene Aliases: 2610306H15Rik; C10orf13; FGF-BP3; FGFBP3; PSEC0101
UniProt ID: (Human) Q8TAT2, (Mouse) Q1HCM0
Entrez Gene ID: (Human) 143282, (Mouse) 72514
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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