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            • Primary Antibodies ›
            • FHL2 Antibodies

            Invitrogen

            FHL2 Monoclonal Antibody (F4B2-B11)

            View all (19) FHL2 antibodies
            Datasheet
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            Catalog # MA1-40200
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            Price (USD)
            982.00
            100 µg
             
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            Cite FHL2 Monoclonal Antibody (F4B2-B11)

            Product Details

            MA1-40200

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:10
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:10
            -

            Immunohistochemistry (Frozen) (IHC (F))

            1:10
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Mouse / IgG1

            Class

            Monoclonal

            Type

            Antibody

            Clone

            F4B2-B11

            Immunogen

            Bacterially-expressed mouse GST-FHL2

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.1 mg/mL

            Purification

            Protein G

            Storage buffer

            PBS with 0.1% BSA

            Contains

            0.02% sodium azide

            Storage conditions

            4°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2104358

            Product Specific Information

            MA1-40200 detects FHL2 from human, mouse, and rat samples.

            MA1-40200 has been successfully used in immunohistochemistry (frozen), immunohistochemistry (paraffin), Western blot, and immunofluorescence applications.

            The MA1-40200 immunogen is human FHL2.

            MA1-40200 recognizes the N-terminal Zn-Finger motif, it does not crossreact in Western Blotting with the FHL1 and FHL3 proteins. MA1-40200 antibody is cross reactive with mouse and rat FHL2.

            Target Information

            This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: aging-associated gene 11; down-regulated in rhabdomyosarcoma LIM protein; FHL-2; Four and a half LIM domains protein 2; LIM domain protein DRAL; OTTHUMP00000203164; OTTHUMP00000203168; OTTHUMP00000203169; Skeletal muscle LIM-protein 3; SLIM 3; SLIM-3

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            Gene Aliases: AAG11; DRAL; FHL-2; FHL2; SLIM-3; SLIM3

            View more View less

            UniProt ID: (Human) Q14192, (Mouse) O70433, (Rat) O35115

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            Entrez Gene ID: (Human) 2274, (Mouse) 14200, (Rat) 63839

            View more View less

            Function(s)

            transcription coactivator activity protein binding transcription factor binding zinc ion binding identical protein binding androgen receptor binding metal ion binding transcription cofactor

            Process(es)

            negative regulation of transcription from RNA polymerase II promoter osteoblast differentiation transcription, DNA-templated response to hormone androgen receptor signaling pathway negative regulation of apoptotic process positive regulation of transcription, DNA-templated atrial cardiac muscle cell development ventricular cardiac muscle cell development heart trabecula formation regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter negative regulation of transcription, DNA-templated
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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