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Product Details
PA5-51470
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FKBP25. Recombinant protein control fragment (Product #RP-88925).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641655
Product Specific Information
Immunogen sequence: LPKKDIIKFL QEHGSDSFLA EHKLLGNIKN VAKTANKDHL VTAYNHLFET KRFKGTESIS KVSEQVKNVK LNEDKPKETK SEETLDEGPP KYTKSVLKKG DKTNFPKKGD VVHCWYTGTL QDGT
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 94%.
Target Information
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 25 kDa FK506-binding protein; 25 kDa FKBP; FK506 binding protein 3, 25kDa; FK506-binding protein 25, T-cell; FK506-binding protein 3; FK506-binding protein 3 (25kD); FKBP-25; FKBP-3; Immunophilin FKBP25; Peptidyl-prolyl cis-trans isomerase FKBP3; PPIase FKBP3; rapamycin binding protein; Rapamycin-selective 25 kDa immunophilin; Rotamase
Gene Aliases: 25kDa; FKBP-25; FKBP-3; FKBP25; FKBP3; PPIase
UniProt ID: (Human) Q00688, (Mouse) Q62446
Entrez Gene ID: (Human) 2287, (Mouse) 30795, (Rat) 299104
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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