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Product Details
PA5-96573
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human FKBP38/FKBP38/FKBP8 (NP_0363133)
Conjugate
Unconjugated
Form
Liquid
Concentration
1.35 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808375
Product Specific Information
Immunogen sequence: QPPAEEAEQP GALAREFLAA MEPEPAPAPA PEEWLDILGN GLLRKKTLVP GPPGSSRPVK GQVVTVHLQT SLENGTRVQE EPELVFTLGD CDVIQALDLS VPLMDVGETA MVTADSKYCY GPQGSRSPYI PPHAALCLEV TLKTAVDGPD LEMLTGQERV ALANRKRECG NAHYQRADFV LAANSYDLAI KAITSSAKVD MTFEEEAQLL Q; Positive Samples: Jurkat, THP-1, BT-474, HeLa, HL-60, Mouse liver, Mouse brain, Mouse eye, Rat brain; Cellular Location: Cytoplasmic side, Mitochondrion membrane, Single-pass membrane protein
Target Information
FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, it does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 38 kDa FK506-binding protein; 38 kDa FKBP; FK506 binding protein 8, 38kDa; FK506-binding protein 38; FK506-binding protein 8; FK506-binding protein 8 (38kD); FKBP-38; FKBP-8; FKBPR38; hFKBP38; mFKBP38; Peptidyl-prolyl cis-trans isomerase FKBP8; PPIase FKBP8; Rotamase
Gene Aliases: 38kDa; FKBP-38; FKBP-8; FKBP38; FKBP8; FKBPr38; Sam11
UniProt ID: (Human) Q14318, (Rat) Q3B7U9, (Mouse) O35465
Entrez Gene ID: (Human) 23770, (Rat) 290652, (Mouse) 14232
protein peptidyl-prolyl isomerization
cell fate specification
apoptotic process
smoothened signaling pathway
viral process
dorsal/ventral neural tube patterning
positive regulation of BMP signaling pathway
multicellular organism growth
intracellular signal transduction
camera-type eye development
negative regulation of apoptotic process
chaperone-mediated protein folding
dorsal/ventral pattern formation
regulation of gene expression
neural tube development
regulation of BMP signaling pathway
protein folding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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