Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPLLNWVALK PSQITGTVFT ELNDEKVLQE LDMSDFEEQF KTKSQGPSLD LSALKSKAAQ KAPSKATLIE ANRAKNLAIT LRKGNLGAER ICQAIEAYDL QALGLDFLEL LMRFLPTEYE RSLITRFERE QRPMEELSEE DRFMLCFSRI PRLPERMTTL TFLGNFPDTA QLLMPQLNAI IAASMSIKSS DKLRQILEIV LAFGNYMNSS KRGAAYGFRL QSLDALLEMK STDRKQTLLH YLVKVIAEKY PQLTGFHSDL HFLDKAGSVS LDSVLADVRS LQRGLELTQR EFVRQDDCMV LKEFLRANSP TMDKLLADSK TAQEAFESVV EYFGENPKTT SPGLFFSLFS RFIKAYKKAE QEVEQWKKEA AAQEAGADTP GKGEPPAPKS PPKARRPQMD LISELKRRQQ KEPLIYESDR DGAIEDIITD LRNQPYIRAD TGRRSARRRP PGPPLQVTSE VSL
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CLL-associated antigen KW-13; formin-like 1; Formin-like protein 1; Leukocyte formin
Gene Aliases: C17orf1; C17orf1B; FHOD4; FMNL; FMNL1; FRL1; KW-13
UniProt ID: (Human) O95466
Entrez Gene ID: (Human) 752
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