Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence of this protein is as follows: QLTGFHSDLH FLDKAGSVSL DSVLADVRSL QRGLELTQRE FVRQDDCMVL KEFLRANSPT MDKLLADSKT AQEAFESVVE YFGENPKTTS PGLFFSLFS
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
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Protein Aliases: CLL-associated antigen KW-13; formin-like 1; Formin-like protein 1; Leukocyte formin
Gene Aliases: C17orf1; C17orf1B; FHOD4; FMNL; FMNL1; FRL1; KW-13
UniProt ID: (Human) O95466
Entrez Gene ID: (Human) 752
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