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Application
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FOXE1 Antibody (PA5-27143) in WB
Western Blot using FOXE1 Polyclonal Antibody (Product # PA5-27143). Sample (30 µg of whole cell lysate). A: HeLaS3. 10% SDS PAGE. FOXE1 Polyclonal Antibody (Product # PA5-27143) diluted at 1:1,000.
Product Details
PA5-27143
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 311 and 373 of FOXE1
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2544619
Product Specific Information
Recommended positive controls: HeLaS3.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: forkhead box E2; Forkhead box protein E1; Forkhead box protein E2; forkhead, drosophila, homolog-like 15; Forkhead-related protein FKHL15; HFKH4; HFKL5; HNF-3/fork head-like protein 5; Thyroid transcription factor 2; TTF-2
Gene Aliases: FKHL15; FOXE1; FOXE2; HFKH4; HFKL5; NMTC4; TITF2; TTF-2; TTF2
UniProt ID: (Human) O00358
Entrez Gene ID: (Human) 2304
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
thyroid hormone generation
anatomical structure morphogenesis
cell migration
thyroid gland development
hair follicle morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
thymus development
embryonic organ morphogenesis
hard palate development
soft palate development
pharynx development
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