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Product Details
CL488-27707
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FTSJD2 fusion protein Ag26722
Conjugate
CoraLite® Plus 488
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SNESHCSLQ IKALAKIHAF VQDTTLSEPR QAEIRKECLR LWGIPDQARV APSSSDPKSK FFELIQGTEI DIFSYKPTLL TSKTLEKIRP VFDYRCMVSG SEQKFLIGLG KSQIYTWDGR QSDRWIKLDL KTELPRDTLL SVEIVHELKG EGKAQRKISA IHILDVLVLN GTDVREQHFN QRIQLAEKFV KAVSKPSRPD MNPIRVKEVY RLEEMEKIFV RLEMKIIKGS SGTPKLSYTG RDDRHFVPMG LYIVRTVNEP WTMGFSKSFK KKFFYNKKTK DSTFDLPADS IAPFHICYYG RLFWEWGDGI RVHDSQKPQD QDKLSKEDVL SFIQMHRA
Target Information
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cap methyltransferase 1; Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; Cap1 2'O-ribose methyltransferase 1; FtsJ methyltransferase domain containing 2; FtsJ methyltransferase domain-containing protein 2; Interferon-stimulated gene 95 kDa protein; ISG95; MTr1; S-adenosyl-L-methionine-dependent methyltransferase FTSJD2
Gene Aliases: 1300018I05Rik; AI451264; CMTR1; FTSJD2; hMTr1; KIAA0082; mKIAA0082; MTR1
UniProt ID: (Human) Q8N1G2, (Mouse) Q9DBC3
Entrez Gene ID: (Human) 23070, (Mouse) 74157
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