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This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.
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Protein Aliases: DNA helicase V; far upstream element (FUSE) binding protein 1; far upstream element (FUSE) binding protein 4; Far upstream element-binding protein 1; far upstream element-binding protein 1 {ECO:0000250|UniProtKB:Q96AE4, ECO:0000312|EMBL:AAI07943.1}; FBP; FBP {ECO:0000250|UniProtKB:Q96AE4}; fubp1 {ECO:0000312|EMBL:AAI07943.1, ECO:0000312|RGD:1591892}; FUSE binding protein 1; FUSE-binding protein 1; FUSE-binding protein 1 {ECO:0000250|UniProtKB:Q96AE4}; hDH V
Gene Aliases: 9530027K12Rik; D3Ertd330e; FBP; FUBP; FUBP1; Fubp4; hDH V
UniProt ID: (Human) Q96AE4, (Rat) Q32PX7
Entrez Gene ID: (Human) 8880, (Rat) 654496, (Mouse) 51886
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