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            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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            • Primary Antibodies ›
            • FUT11 Antibodies

            Invitrogen

            FUT11 Polyclonal Antibody

            View all (3) FUT11 antibodies
            Datasheet
            Protocols
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            Tech Support
            Catalog # PA5-53114
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            100 µL
             
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            Cite FUT11 Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            FUT11 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            FUT11 Antibody (PA5-53114) in ICC/IF

            Immunofluorecent analysis of FUT11 in human cell line A-431 using FUT11 Polyclonal Antibody (Product # PA5-53114). Staining shows localization to nuclear membrane and the Golgi apparatus.
            View Product

            FUT11 Antibody in Immunocytochemistry (ICC/IF)
            FUT11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

            Product Details

            PA5-53114

            Applications
            Tested Dilution
            Publications

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:200
            -

            Immunocytochemistry (ICC/IF)

            0.25-2 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein corresponding to Human FUT11. Recombinant protein control fragment (Product #RP-90784).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.2 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.2, with 40% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2641787

            Product Specific Information

            Immunogen sequence: MKYLAYKQPG GITNQFLLDS LKHREWGVND PLLPNYLNGF ECFVCDYELA RLDAEKAHAA SPGDSPVFEP HIAQPSHMDC PVPTPGFGNV EEIPENDSWK EMWLQDYWQG LDQGEALTAM IHNNETEQTK FWDYL

            Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.

            Target Information

            The FUT11 gene encodes for fructosyltransferase 11, an enzyme that is part of the glycosyltransferase family involved in the modification of glycoproteins and glycolipids by catalyzing the addition of fucose moieties. Enzymes like FUT11 play a critical role in the biosynthesis of Lewis antigen structures, significantly contributing to cell-cell adhesion, signal transduction, and immune recognition. Fucosylation, the process mediated by fructosyltransferases, is crucial for various biological functions, including the regulation of leukocyte trafficking and selectin binding, emphasizing its importance in immune responses and inflammation. While FUT11 is less characterized compared to other fucosyltransferases, altered expression patterns and functional abnormalities in these enzymes are linked to pathological conditions, such as cancer and inflammatory diseases, where changes in glycosylation can affect tumor progression, metastasis, and immune evasion. Ongoing research into FUT11 aims to elucidate its specific role in cellular processes and explore potential therapeutic applications by targeting fucosylation pathways to modify disease progression.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: alpha (1,3) fucosyltransferase; Alpha-(1,3)-fucosyltransferase 11; EC 2.4.1; Fuc-TXI; Fucosyltransferase 11; fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Fucosyltransferase XI; fucT-XI; Galactoside 3-L-fucosyltransferase 11; MGC119338; MGC119339; MGC33202

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            Gene Aliases: FUT11

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            UniProt ID: (Human) Q495W5

            View more View less

            Entrez Gene ID: (Human) 170384

            View more View less

            Function(s)

            protein binding alpha-(1->3)-fucosyltransferase activity glycosyltransferase

            Process(es)

            protein N-linked glycosylation fucosylation
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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