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            • Primary Antibodies ›
            • FZD1 Antibodies

            Invitrogen

            FZD1 Polyclonal Antibody

            View all (10) FZD1 antibodies

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            Datasheet
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            Catalog # PA5-95287
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            Price (USD)
            477.00
            100 µg
             
            Estimated availability date: 07-Jul-2025
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            Cite FZD1 Polyclonal Antibody

            Product Details

            PA5-95287

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.1-0.5 µg/mL
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            0.5-2 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            A synthetic peptide corresponding to a sequence at the C-terminus of human Frizzled homolog 1 (369-400aa YIAGFLLEDRVVCNDKFAEDGARTVAQG TKKE).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Lyophilized

            Concentration

            500 µg/mL

            Purification

            Affinity chromatography

            Storage buffer

            PBS with 5mg BSA

            Contains

            0.05mg sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2807091

            Product Specific Information

            Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

            Positive Control - WB: 22RV1 whole cell, 293T whole cell. IHC: human prostatic cancer tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

            Target Information

            Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: Chfz-1; Dfrizzled-1; DKFZp564G072; FLJ95923; frizzled; frizzled 1; frizzled 1, seven transmembrane spanning receptor; frizzled family receptor 1; frizzled homolog 1; frizzled, Drosophila, homolog of, 1; Frizzled-1; Fz receptor 1; Fz-1; FzE1; hFz1; Wnt receptor; Xfrizzled-1

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            Gene Aliases: FZD1

            View more View less

            UniProt ID: (Human) Q9UP38

            View more View less

            Entrez Gene ID: (Human) 8321

            View more View less

            Function(s)

            G-protein coupled receptor activity receptor binding frizzled binding protein binding Wnt-protein binding PDZ domain binding Wnt-activated receptor activity transmembrane signal receptor

            Process(es)

            positive regulation of protein phosphorylation membranous septum morphogenesis muscular septum morphogenesis outflow tract morphogenesis G-protein coupled receptor signaling pathway cell-cell signaling synapse assembly neuron differentiation negative regulation of BMP signaling pathway epithelial cell differentiation negative regulation of catenin import into nucleus autocrine signaling non-canonical Wnt signaling pathway response to drug canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation canonical Wnt signaling pathway involved in osteoblast differentiation regulation of osteoblast differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated lung alveolus development positive regulation of sequence-specific DNA binding transcription factor activity hard palate development canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway cellular response to vitamin D cellular response to growth factor stimulus cellular response to peptide hormone stimulus negative regulation of canonical Wnt signaling pathway planar cell polarity pathway involved in neural tube closure beta-catenin destruction complex disassembly Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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