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Application
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FZD3/Frizzled 3 Antibody (BS-13239R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded human colon cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with Rabbit Anti-FZD3/Frizzled 3 Polyclonal Antibody, Unconjugated ( bs-13239R ) at 1:200 overnight at 4°C, followed by the secondar... View More
Product Details
BS-13239R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human FZD3/Frizzled 3, amino acids 121-220.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frizzled 3; frizzled 3, seven transmembrane spanning receptor; frizzled family receptor 3; frizzled homolog 3; Frizzled-3; Fz-3; hFz3; mFz3
Gene Aliases: AU020229; D930050A07Rik; Fz-3; Fz3; FZD3
UniProt ID: (Human) Q9NPG1, (Mouse) Q61086
Entrez Gene ID: (Human) 7976, (Mouse) 14365, (Rat) 266715
establishment of planar polarity
neuron migration
neural tube closure
hair follicle development
positive regulation of neuroblast proliferation
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
neuron differentiation
cell proliferation in midbrain
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
dopaminergic neuron axon guidance
serotonergic neuron axon guidance
inner ear morphogenesis
negative regulation of mitotic cell cycle, embryonic
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
sympathetic ganglion development
commissural neuron axon guidance
negative regulation of execution phase of apoptosis
midbrain morphogenesis
signal transduction
cell surface receptor signaling pathway
multicellular organism development
nervous system development
Wnt signaling pathway
midbrain development
brain development
response to drug
response to electrical stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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