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Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25 kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 28 kDa adipocyte protein; Adipsin; C3 convertase activator; Complement factor D; D component (adipsin) of complement; EC 3.4.21.46; Properdin factor D
Gene Aliases: Adn; Cfd; DF
UniProt ID: (Mouse) P03953
Entrez Gene ID: (Mouse) 11537
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