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Invitrogen
Ficolin 3 Monoclonal Antibody (296134)
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Product Details
MA5-24004
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
296134
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Ficolin-3 Isoform 2 Lys22-Arg288
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610025
Product Specific Information
In direct ELISAs and Western blots, no cross-reactivity with recombinant human Ficolin-2 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collagen/fibrinogen domain-containing lectin 3 p35; Collagen/fibrinogen domain-containing protein 3; Ficolin-3; Hakata antigen; MGC22543
Gene Aliases: FCN3; FCNH; HAKA1
UniProt ID: (Human) O75636
Entrez Gene ID: (Human) 8547
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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