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This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
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Protein Aliases: GABA(A) receptor subunit gamma-2; GABA(A) receptor, gamma 2; GABAAR subunit gamma-2; GABRA2; gamma-aminobutyric acid; gamma-aminobutyric acid A receptor, gamma 2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2; gamma-aminobutyric acid A receptor, gamma 2; Gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid type A receptor gamma2 subunit
Gene Aliases: CAE2; ECA2; GABAA-R; Gabrg-2; GABRG2; gamma2; GEFSP3
UniProt ID: (Human) F5HB82, (Mouse) P22723, (Rat) P18508
Entrez Gene ID: (Human) 2566, (Rabbit) 100357302, (Mouse) 14406, (Rat) 29709
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