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Application
FIGURE: 1 / 6
GALNS Antibody (14933-1-AP) in IHC (P)
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using (Product # 14933-1-AP) (GALNS antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Product Details
14933-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GALNS Fusion Protein Ag6746 (174-522 aa encoded by BC050684)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ARPNIPVYR DWEMVGRYYE EFPINLKTGE ANLTQIYLQE ALDFIKRQAR HHPFFLYWAV DATHAPVYAS KPFLGTSQRG RYGDAVREID DSIGKILELL QDLHVADNTF VFFTSDNGAA LISAPEQGGS NGPFLCGKQT TFEGGMREPA LAWWPGHVTA GQVSHQLGSI MDLFTTSLAL AGLTPPSDRA IDGLNLLPTL LQGRLMDRPI FYYRGDTLMA ATLGQHKAHF WTWTNSWENF RQGIDFCPGQ NVSGVTTHNL EDHTKLPLIF HLGRDPGERF PLSFASAEYQ EALSRITSVV QQHQEALVPA QPQLNVCNWA VMNWAPPGCE KLGKCLTPPE SIPKKCLWSH (174-522 aa encoded by BC050684)
Target Information
This gene encodes N-acetylgalactosamine-6-sulfatase whichis a lysosomal exohydrolase required for the degradation of theglycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate.Sequence alterations including point, missense and nonsensemutations, as well as those that affect splicing, result in adeficiency of this enzyme. Deficiencies of this enzyme lead toMorquio A syndrome, a lysosomal storage disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chondroitinase; Chondroitinsulfatase; galactosamine (N-acetyl)-6-sulfate sulfatase; Galactose-6-sulfate sulfatase; GalN6S; GalNAc6S sulfatase; N-acetylgalactosamine-6-sulfatase; N-acetylgalactosamine-6-sulfate sulfatase
Gene Aliases: GalN6S; GALNAC6S; GALNS; GAS; mFLJ00319; MPS4A
UniProt ID: (Human) P34059, (Mouse) Q571E4, (Rat) Q32KJ6
Entrez Gene ID: (Human) 2588, (Mouse) 50917, (Rat) 292073
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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