Proteintech

GAP43 Polyclonal Antibody

GAP43 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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GAP43 Antibody (16971-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using (Product # 16971-1-AP) (GAP43 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

GAP43 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

16971-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:600-1:3000

View 25 publications 25 publications

Immunohistochemistry (IHC)

View 7 publications 7 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 11 publications 11 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GAP43 Fusion Protein Ag9294 (1-238 aa encoded by BC007936)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MLCCMRRTK QVEKNDDDQK IEQDGIKPED KAHKAATKIQ ASFRGHITRK KLKGEKKDDV QAAEAEANKK DEAPVADGVE KKGEGTTTAE AAPATGSKPD EPGKAGETPS EEKKGEGDAA TEQAAPQAPA SSEEKAGSAE TESATKASTD NSPSSKAEDA PAKEEPKQAD VPAAVTAAAA TTPAAEDAAA KATAQPPTET GESSQAEENI EAVDETKPKE SARQDEGKEE EPEADQEHA (1-238 aa encoded by BC007936 )

Target Information

GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; growth accentuating protein 43; Growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1

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Gene Aliases: B-50; Basp2; GAP-43; GAP43; PP46

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UniProt ID: (Human) P17677, (Rat) P07936, (Mouse) P06837

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Entrez Gene ID: (Human) 2596, (Rat) 29423, (Mouse) 14432

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Function(s)

phosphatidylserine binding protein binding calmodulin binding lysophosphatidic acid binding phosphatidylinositol phosphate binding

Process(es)

nervous system development axon guidance glial cell differentiation axon choice point recognition regulation of growth tissue regeneration cell fate commitment regulation of filopodium assembly axon development multicellular organism development cell differentiation protein kinase C-activating G-protein coupled receptor signaling pathway response to wounding

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GAP43 Polyclonal Antibody

GAP43 Antibody (16971-1-AP) in IHC (P)

Product Details

16971-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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